Treatment of ureaplasma in women consists of complex measures, the choice of which is based on the localization of inflammation. For general therapy, antibacterial drugs are used, the purpose of which is to eliminate the infection; correctors of immunity, initiating its work; drugs to reduce the risk of side effects from antibiotic use.
A clear treatment regimen for ureaplasma in women is determined only by a doctor who has all the information about the patient. Usually, experts recommend suppressing the ureaplasma if a woman has an infectious-inflammatory process, for example, with cervicitis or vaginitis. In addition, this measure of combating ureaplasma is carried out with childlessness, the risk of miscarriage , diseases of the pelvic organs of an inflammatory nature, states of fever due to the presence of ureaplasma in the genitourinary system.
Treatment of ureaplasma in women of etiotropic nature is based on the use of antibacterial agents of all kinds of groups. The effectiveness of this treatment is determined in laboratory studies by the extremely low inhibitory concentration. In theory, antibiotics with an extremely low concentration of suppression should be the best drugs. Nevertheless, one should not forget about such important criteria of the drug as bioavailability, the ability to form strong concentrations inside tissues and cells.
The microorganism ureaplasma tolerates beta- lactam antibiotics, for example, penicillin, due to the fact that these bacteria do not have cell walls, and sulfa drugs because the bacteria do not secrete acid. In the process of treating ureaplasma in women, those antibacterial drugs that affect the formation of protein from human DNA give a positive result. These drugs belong to the group of tetracyclines, for example, chloramphenicol and other drugs.
Of all the antibiotics of the tetracycline group, dioxycycline and minocycline are considered the most convenient to use , since it is these drugs that can be used once or twice a day.
In accordance with the developed recommendations for the use of drugs, in the treatment of ureaplasma in women, dioxycycline should be prescribed , that is, drugs such as unidox and solutab , medomycin and vibramycin . These drugs are prescribed 100 mg tablets 2 times a day for one or two weeks. As a rule, a double dose of the drug is taken in the first oral administration.
A positive effect is observed with the use of dioxycycline in women infected with all kinds of mycoplasmas and who have childlessness or primary miscarriage . After a course of treatment for mycoplasma infection, in some cases, a woman becomes capable of conception, which ends with resolution on time and without any difficulties.
It must be said that from 1% to 30% of the varieties of microorganisms of ureaplasma are characterized by resistance to drugs of the tetracycline group. Another significant disadvantage of tetracycline is the presence of contraindications such as pregnancy and its use for the treatment of children under the age of 9 years. In addition, side effects of tetracycline are disorders of the gastrointestinal tract, as well as hypersensitivity of the skin to the sun.
In case of infection of newborns infected with ureaplasma in the womb, erythromycin therapy is prescribed. Intravenous administration of the drug is recommended at the rate of 20-30 mg per kilogram of body weight.